SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination. Nature. 2015 Dec 23.
High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities. Cell. 2015 Dec 3;163(6):1515-26.
Panorama of ancient metazoan macromolecular complexes. Nature. 2015 Sept 17;525:339-344.
RNA SPLICING. An alternative splicing event amplifies evolutionary differences between vertebrates. Science. 2015 Aug 21;349(6250):868-73.
Driving Innovation in Medicine
Discoveries made in basic science are the foundation for all future progress in medicine. Emerging genomic and stem cell technologies hold the promise of personalized treatments that are tailored to patient’s unique genetic makeup and physiology. Through our collaborative approach, the Donnelly Centre is in a position to make breakthrough discoveries in biology and to lead the world in advancing personalized medicine.
Your gift to the Donnelly Centre allows researchers to explore new and innovative ideas that will transform our understanding of biology. It supports discovery that will unearth the cause of human disease, advance diagnosis and disease detection, create personalized therapies, and reverse injury through regenerative medicine.